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Cat No. | Product Name | Synonyms | Targets |
---|---|---|---|
T67899 | Topoisomerase II inhibitor 13 | Topoisomerase | |
Topoisomerase II inhibitor 13 inhibits topoisomerase II (Topo II) that shows strong anti-proliferation activity against HL-60/MX2 cancer cells derived from HL-60 against Topo II toxicity. | |||
T77650 | Topoisomerase II inhibitor 14 | Apoptosis , Antioxidant , Topoisomerase , NO Synthase | |
Topoisomerase II inhibitor 14 is a potent topoisomerase II inhibitor with anticancer and antioxidant activities.Topoisomerase II inhibitor 14 induces apoptosis and blocks the cell cycle in S phase.Topoisomerase II inhibi... | |||
T26046 | Razoxane | Topoisomerase | |
Razoxane is used as an antimitotic agent with immunosuppressive properties. | |||
T64047 | Topoisomerase II inhibitor 10 | ||
Topoisomerase II inhibitor 10 is a potent inhibitor of topoisomerase II (IC50: 7.45 μM). Topoisomerase II inhibitor 10 was able to arrest the cell cycle of HepG-2 cells in the G2-M phase and induce apoptosis. | |||
T62887 | Topoisomerase II inhibitor 4 | ||
Topoisomerase II inhibitor 4 (compound E17) is a potent inhibitor of topoisomerase II. Topoisomerase II inhibitor 4 has antitumour effects, blocking the cell cycle in the G2/M phase, inhibiting the proliferation of cance... | |||
T63304 | Topoisomerase II inhibitor 9 | ||
Topoisomerase II inhibitor 9 is a Topo II inhibitor (IC50: 0.97 μM) and DNA embedding agent (IC50: 43.51 μM) that blocks the Hep G-2 cell cycle in the G2/M phase and induces apoptosis. | |||
T79506 | Topoisomerase II inhibitor 15 | Topoisomerase | |
Topoisomerase II inhibitor 15 (compound 2g) serves as a potent apoptotic inducer, exhibiting heightened selectivity for head and neck tumors [1]. | |||
T60781 | Topoisomerase II inhibitor 8 | ||
Topoisomerase II inhibitor 8 (compound 22) shows good anti-proliferative activities and arrest the cell cycle at G2/M phase. Topoisomerase II inhibitor 8 is a potent inhibitor of topoisomerase II (IC 50 = 0.52 μM) [1]. | |||
T72157 | Topoisomerase II inhibitor 7 | ||
Topoisomerase II inhibitor 7, a potent inhibitor of the topoisomerase II alpha subtype, exhibits an IC50 of 3.19 μM. It effectively induces cell cycle arrest and apoptosis. | |||
T61017 | Topoisomerase II inhibitor 6 | ||
Topoisomerase II inhibitor 6 (Compound 5) is a tryptanthrin derivative. Topoisomerase II inhibitor 6 is a potent and selective topoisomerase II inhibitor. Topoisomerase II inhibitor 6 blocks the CCRF-CEM cell cycle in th... | |||
T64164 | Topoisomerase II inhibitor 11 | ||
Topoisomerase II inhibitor 11 (compound 3d) is a potent inhibitor of Topoisomerase II (IC50: 2.89 μM). Topoisomerase II inhibitor 11 inhibits cell proliferation and has apoptotic activity by blocking the cell cycle in th... | |||
T63068 | Topoisomerase II inhibitor 5 | ||
Topoisomerase II inhibitor 5 (Compound E24) is a DNAtopoisomerase II inhibitor with anticancer effects. | |||
T61283 | Topoisomerase II inhibitor 3 | ||
Topoisomerase II inhibitor 3 (Compound 6 h) is an acridone derivative that acts as a Type II DNA topoisomerase (topo II) inhibitor. It specifically inhibits the topo IIα/β subtypes, with an IC50 value of 0.17 μM for topo... | |||
T79539 | Topoisomerase II inhibitor 16 | Topoisomerase | |
Topoisomerase II Inhibitor 16 (compound CT3) is a selective, orally bioavailable, and irreversible inhibitor of trypanosomal topoisomerase II, possessing the ability to penetrate the brain and stabilize double-stranded D... | |||
T61990 | Topoisomerase I/II inhibitor 3 | ||
Topoisomerase I/II inhibitor 3 (compound 7) is a potent dual inhibitor of topoisomerase I (Topo I) and II (Topo II) . By inhibiting PI3K /Akt/mTOR signaling pathway, Topoisomerase I/II inhibitor 3 can inhibit cell prolif... | |||
T63526 | Topoisomerase I/II inhibitor 4 | ||
Topoisomerase I/II inhibitor 4 is a potent dual inhibitor of topoisomerase I (Topo I) and II (Topo II) with inhibitory effects on cell proliferation, invasion and migration, and induction of apoptosis, and can be used to... | |||
T61045 | Topoisomerase I/II inhibitor 2 | ||
Topoisomerase I/II inhibitor 2 (compound 1a) can significantly reduce the xenograft tumor growth in mice model which can be used in treating liver cancer. Topoisomerase I/II inhibitor 2 is a DNA topoisomerase I/II dual i... | |||
T63360 | DNA topoisomerase II inhibitor 1 | ||
DNA topoisomerase II inhibitor 1 is a potent inhibitor of DNA topoisomerase II that arrests the cell cycle in sub-G1 phase and induces apoptosis with anti-value-added effects. | |||
T61054 | Type II topoisomerase inhibitor 1 | ||
Type II topoisomerase inhibitor 1 is able to be used in the antibacterial area. Type II topoisomerase inhibitor 1 is a potent and selective inhibitor of E. coli DNA gyrase with a IC50 value of 1.7 nM as well as forms hyd... | |||
T3481 | Bimolane | Topoisomerase | |
Bimolane is a topoisomerase II inhibitor. |